Abstract
The aim of this study was to evaluate the inhibitory effects of oral moisturising gel containing egg yolk antibody against Candida albicans (anti-CA IgY) in older people. Therefore, we measured the number of Candia CFU present on oral swabs at baseline and after using the gel. A randomised, double-blind, placebo-controlled trial was conducted among volunteers living in a nursing home in Japan. The participants were divided into two groups. The group 1 participants received oral care using an experimental oral moisturising gel with anti-CA IgY, and those in group 2 received oral care using a placebo oral moisturising gel without anti-CA IgY. The oral care was performed by care workers three times a day for 4weeks. The participants' tongues were sampled using a swab method at baseline and after 2 and 4weeks of using the oral gel, and the number of C.albicans, Candida tropicalis and Candida krusei colonies was counted. The baseline oral condition of the participants in the two groups did not differ significantly. The experimental gel significantly reduced the number of C.albicans colonies from baseline to after 4weeks of using the oral gel; however, no significant reductions were observed in the number of C.tropicalis or C.krusei colonies. The use of oral moisturising gel containing anti-CA IgY for 1month significantly reduces the number of C.albicans CFU present on swabs in older people.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
