Abstract
This study was aimed to know the effect of giving shallot extract (Allium ascalonicum L) to histopathological feature of rat (Rattus norvegicus) liver induced by alloxan. Alloxan was intraperitoneally injected 120 mg/ kg BW (single dose). A total of twenty male Wistar rats of three months old were used in the study. The rats were divided into five groups. 1) negative control group (K-) treated by CMC Na 0.5 %, 2) positive control group (K+) treated by metformin 45 mg/kg BW as a standard drug, 3) extract of Allium ascalonicum 250 mg/kg BW (P1), 4) extract of Allium ascalonicum 500 mg/kg BW (P2), 5) extract of Allium ascalonicum 750 mg/kg BW (P3). Rats were treated for 14 days. The data of this study were analyzed by Kruskal Wallis Test, then it continued by Mann-Whitney Test. The result of this study is Allium ascalonicum can improve the histopathological feature of rats liver induced by alloxan.
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