Abstract
The increase in skeletal calcification associated with the onset of laying in the pullet is accompanied by several well defined changes in the blood picture (Sturkie, 19S4). The association of these changes with endogenous gonadal hormone output can be inferred from a study of serum constituents following the administration of these hormones to sexually immature fowls and comparison of the blood picture with that of the laying hen.Since alkaline phosphatase is considered to be formed in the bones, it is likely that increases in skeletal calcification will be accompanied by changes in the serum levels of alkaline phosphatase. Early work on the serum alkaline phosphatase activity in laying hens by Common (1936) showed that large variations occurred between hens and between sera obtained from individual birds. Recently, Bell (1960) has shown that immature birds of both sexes have plasma alkaline phosphatase levels up to ten times those found in…
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