Abstract
Objective To observe the effects of ozone nucleus pulposus ablation on blood pressure, heart rate and oxygen saturation in patients during the treatment of lumbar disc herniation. Methods Fifty-four patients with lumbar disc herniation in Guizhou Orthopedics Hospital from January 2016 to October 2017, aged 37-60 years old, were treated by injection ozone (70 μg/ml) into intervertebral disc at the rate of 1ml/s for 5 ml. The blood pressure, heart rate and oxygen saturation were observed and recorded at the beginning of treatment, injection of ozone and 1, 5, 10 min after the injected. Results Compared with the beginning of the treatment, the heart rate decreased significantly at 1 min after the injection of ozone (P 0.05). No difference was found in blood pressure and oxygen saturation at the time of ozone injection and 1, 5, 10 minutes after the injection (P>0.05). Conclusion Nucleus pulposus ablation may cause temporary decline of heart rate during the injection of ozone into intervertebral disc in the treatment of patients with lumbar disc herniation, but no significant effect on blood pressure and oxygen saturation. Key words: Ozone; Lumbar vertebrae; Intervertebral disc displacement; Heart rate; Blood pressure
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