Abstract
Cipangopaludina chinensis were exposed to different concentrations of Nonylphenol (NP) in experimental groups. The effects of NP on the enzyme activity of erythromycin N-demethylase (ERND) in stomach were studies. The result showed that different concentrations of NP in settlings had different influence on the enzyme activity of ERND. The overall trend was that the activity of enzyme ERND showed decrease tendency at the beginning, then increased. Later, the enzyme activity of ERND in the stomach in the median concentration and high concentration was higher than Group Ⅲ (Environment group). Consolidating half-lethal concentration measurement results NP was shown that it has toxicity, so its impact on the environment can not be ignored.
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