Effects of noncarbohydrate substrates on protein synthesis in muscle.

Abstract

ARTICLESEffects of noncarbohydrate substrates on protein synthesis in muscleDE Rannels, AC Hjalmarson, and HE MorganDE Rannels, AC Hjalmarson, and HE MorganPublished Online:01 Mar 1974https://doi.org/10.1152/ajplegacy.1974.226.3.528MoreSectionsPDF (3 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByThe insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α1-adrenergic receptors8 June 2021 | Biochemical Journal, Vol. 478, No. 11Autophagy in heart disease: A strong hypothesis for an untouched metabolic reserveMedical Hypotheses, Vol. 77, No. 1Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3′-azido-3′-deoxythymidine-dependent cardiotoxicity27 August 2009 | Biochemical Journal, Vol. 422, No. 3Elevated plasma free fatty acids decrease basal protein synthesis, but not the anabolic effect of leucine, in skeletal muscleCharles H. 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Morgan1 September 1980 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 239, No. 3Effects of diabetes on protein synthesis in fast- and slow-twitch rat skeletal muscleK. E. Flaim, M. E. Copenhaver, and L. S. Jefferson1 July 1980 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 239, No. 1Regulation of protein synthesis and degradation during in vitro cardiac workH. E. Morgan, B. H. Chua, E. O. Fuller, and D. Siehl1 May 1980 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 238, No. 5Production of alanine and glutamine by atrial muscle from fed and fasted ratsM. E. Tischler, and A. L. Goldberg1 May 1980 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 238, No. 5Alterations in metabolism following injury: part IIInjury, Vol. 11, No. 4Suppression of myocardial protein degradation in the rat during fasting. Effects of insulin, glucose, and leucine.Circulation Research, Vol. 46, No. 4METABOLISM IN MUSCLEEffect of leucine and metabolites of branched chain amino acids on protein turnover in heart.Journal of Biological Chemistry, Vol. 254, No. 17Inhibition of protein degradation by anoxia and ischemia in perfused rat hearts.Journal of Biological Chemistry, Vol. 254, No. 14The effect of chronic protein-calorie undernutrition in the rat on myocardial function and cardiac function.Circulation Research, Vol. 45, No. 1The Metabolic Response to Injury and Its Nutritional Implications: Retrospect and Prospect6 September 2016 | Journal of Parenteral and Enteral Nutrition, Vol. 3, No. 3PEPTIDE-CHAIN INITIATION IN HEART AND SKELETAL MUSCLEInfluence of amino acid availability on protein turnover in perfused skeletal muscleBiochimica et Biophysica Acta (BBA) - General Subjects, Vol. 544, No. 2Regulation of leucine and alpha-ketoisocaproate metabolism in skeletal muscle.Journal of Biological Chemistry, Vol. 253, No. 22Amino acid transport by a muscle cell lineMuscle AND Nerve, Vol. 1, No. 3Cardiac abnormalities in cachectic patients before and during nutritional repletionAmerican Heart Journal, Vol. 95, No. 5Studies concerning the specificity of the effect of leucine on the turnover of proteins in muscles of control and diabetic ratsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, Vol. 475, No. 1Physical training in manEuropean Journal of Applied Physiology and Occupational Physiology, Vol. 36, No. 3Regulation of Protein Synthesis and Degradation in Heart and Skeletal Muscle1Carbohydrate metabolism in vivo: Regulation of the blood glucose levelClinics in Endocrinology and Metabolism, Vol. 5, No. 3Starvation results in decreased initiation factor activity in rat skeletal muscleBiochemical and Biophysical Research Communications, Vol. 72, No. 4EFFECTS OF ANOXIA AND SEVERE ISCHEMIA ON THE TURNOVER OF MYOCARDIAL PROTEINS*24 April 2009 | Acta Medica Scandinavica, Vol. 199, No. S587Effects of hypophysectomy, growth hormone, and thyroxine on protein turnover in heart.Journal of Biological Chemistry, Vol. 250, No. 12Effect of insulin on protein turnover in heart muscle.Journal of Biological Chemistry, Vol. 250, No. 5The Control of Protein Turnover in the Isolated Perfused Rat Heart**Supported by grant number HE-11534 and contract number NHLI-71-2499, from the National Institutes of Health.PALMITATE AND PROTEIN SYNTHESIS IN CARDIAC MUSCLE27 April 2009 | Nutrition Reviews, Vol. 32, No. 10 More from this issue > Volume 226Issue 3March 1974Pages 528-539 Copyright & PermissionsCopyright © 1974 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1974.226.3.528PubMed4817404History Published online 1 March 1974 Published in print 1 March 1974 Metrics