Abstract

Background and aims: Non-selective β-blockers (NSBBs) have been associated with increased incidence of paracentesis induced circulatory dysfunction (PICD) and reduced survival in patients with cirrhosis and refractory ascites. We have prospectively evaluated intra-individual central and peripheral hemodynamic effects produced by NSBBs introduction and the incidence of PICD in patients undergoing large volume paracentesis (LVP).

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