Abstract
Nicotine injected intravenously (2 μg kg every 30 sec for 30 min) caused an increased release of ( 3H)noradrenaline into the effluent from the perfused third cerebral ventricle of the cat. Similar changes were observed following the administration of cigarette smoke directly into the lungs and after perfusion of the third ventricle with nicotine (2 or 5 μg/ml). An increase in the efflux of ( 3H)noradrenaline also occurred, after perfusion with nicotine (50 μg/ml) of rat hypothalamic tissue slices. These observations are consistent with the hypothesis that nicotine causes release of noradrenaline from the diencephalon, in particular the hypothalamus.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
More From: Biochemical Pharmacology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
