Effects of Native Banana Starch Supplementation on Body Weight and Insulin Sensitivity in Obese Type 2 Diabetics

Jorge L Ble-Castillo,María A Aparicio-Trápala,Arturo Rodríguez-Hernández,José D Méndez,Juan C Díaz-Zagoya,Mateo U Francisco-Luria,Rubén Córdova-Uscanga

doi:10.3390/ijerph7051953

Abstract

Few fiber supplements have been studied for physiological effectiveness. The effects of native banana starch (NBS) and soy milk (control) on body weight and insulin sensitivity in obese type 2 diabetics were compared using a blind within-subject crossover design. Subjects undertook two phases of 4-week supplementation either with NBS or soy milk. Patients on NBS lost more body weight than when they were on control treatment. Plasma insulin and HOMA-I were reduced after NBS consumption, compared with baseline levels, but not significantly when compared to the control treatment. Results support the use of NBS as part of dietary fiber supplementation.

Highlights

The number of people with diabetes worldwide is projected to rise from 171 million in 2000 to 366 million by 2030 [1]
In the course of months or years, Insulin resistance (IR) is accompanied by the increase in β-cell insulin secretion and by different complications known as the insulin resistance syndrome which is associated to dyslipidemia, hypertension, hyperglycemia and cardiovascular disease [4]
Poor glycemic control was observed in most patients, despite their medical management, 85% had glucose values over 126 mg/dL and 42% had HbA1c percentage higher than 7.0

Summary

Introduction

The number of people with diabetes worldwide is projected to rise from 171 million in 2000 to 366 million by 2030 [1]. This expectancy is associated with the increasing prevalence of overweight and obesity. Insulin resistance (IR) is the key mechanism unifying obesity and type 2 diabetes. IR is characterized as the tissues inability to take up glucose in response to insulin. In the course of months or years, IR is accompanied by the increase in β-cell insulin secretion and by different complications known as the insulin resistance syndrome which is associated to dyslipidemia, hypertension, hyperglycemia and cardiovascular disease [4]

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