Abstract
The primary objective of this study was to compare the effects on muscle metabolism of two types of aerobic training, with and without a load on the lower limbs, in adults with peripheral arterial disease (PAD). A simple blind randomized clinical trial was conducted using two groups: conventional aerobic (CG) and modified aerobic with a load on the lower limbs (MG). Both groups underwent training by walking three times a week over a 12-week period. The ratings of muscle metabolism were determined after a treadmill test with constant velocity and inclination concomitant with the use of near infrared spectroscopy (NIRS). Altogether 40 individuals with PAD (CG = 65.45 ± 10.60 and MG = 63.10 ± 10.54) were included in the study. After the intervention, in both groups, there was a reduction in the relative time to recovery (p = 0.002), an improvement in the re-oxygenation rate (p = 0.017), an increased time of resistance after reaching the lowest muscle oxygen saturation (StO2) (p < 0.001), an increase in the distance walked (p < 0.001), and an improvement of the walking economy relative to StO2 (p < 0.001). After 12 weeks of training, an improvement in the deoxygenation rate was observed in both groups (p = 0.002), but with a greater magnitude in the CG (p = 0.017). Only the CG presented an increase in time to reach the lowest StO2 on the treadmill after the intervention (p = 0.010). The traditional aerobic training was superior to the modified training in relation to the improvement of muscle metabolism in patients with PAD.
Highlights
The primary objective of this study was to compare the effects on muscle metabolism of two types of aerobic training, with and without a load on the lower limbs, in adults with peripheral arterial disease (PAD)
The primary objective of this study was to evaluate the effects of a modified training program on muscle metabolism, using walking concomitant with the use of lower limb overload in individuals with peripheral arterial disease, and compare it to traditional aerobic walking with respect to limiting symptoms of ischemia
The present study is innovative as an assessment of the effects on muscle metabolism of overload training on the lower limbs compared to conventional walking, by means of adjustments of the near infrared spectroscopy (NIRS)
Summary
The primary objective of this study was to compare the effects on muscle metabolism of two types of aerobic training, with and without a load on the lower limbs, in adults with peripheral arterial disease (PAD). Along with the use of shin weights in the lower limbs, may be an alternative way of imposing overload functionally, considering that individuals with PAD present with a significant limitation in performance during submaximal activities such as walking[4] This training is a viable therapeutic option in the treatment of individuals with PAD, the effects of this type of program on muscle metabolism have not been described in the literature. The primary objective of this study was to evaluate the effects of a modified training program on muscle metabolism, using walking concomitant with the use of lower limb overload in individuals with peripheral arterial disease, and compare it to traditional aerobic walking with respect to limiting symptoms of ischemia. The hypothesis of the present study was that patients with PAD who performed the modified aerobic with a load on the lower limbs would present greater gains in functional capacity, metabolism and muscular performance than subjects submitted to traditional aerobic walking training
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