Effects of mobile CT and conventional CT scanning on secondary cerebral pathological injury and therapeutic effect following brain trauma

Abstract

Objective To compare the scanning frequencies of patients with severe craniocerebral pathological injury with bedside mobile CT (MCT) in neurosurgical intensive care unit (NICU) or with conventional CT (CCT) in Radiology, and investigate the effects of MCT and CCT scanning on secondary cerebral injury and therapeutic results in patients with severe craniocerebral injury. Methods A total of 1917 patients with severe craniocerebral injury, admitted to our hospital from August 2010 to December 2015, under went MCT bedside scanning. And other 593 patients with severe craniocerebral injury were scanned with CCT in radiology. According to Glasgow coma scale (GCS) scores, the patients with severe craniocerebral injury were divided into extra- heavy subgroup (GCS scores: 3-5) and heavy subgroup (GCS scores: 6-8); the CT scanning frequencies, secondary cerebral pathological damages and Glasgow outcome scale scores 3 months after injury were analyzed and compared. Results The average scanning frequencies of MCT were 5.12 and 4.88 in patients from extra- heavy subgroup and heavy subgroup while the average scanning frequencies of CCT were 3.53 and 4.08 in patients from extra-heavy subgroup and heavy subgroup, with significant differences (P< 0.05); patients accepted MCT had significantly higher scanning frequencies than those accepted CCT (P<0.05). The average scanning frequencies of patients from MCT group were significantly higher than those from CCT group. The incidence of complications was 3.32% and 0% in extra-heavy subgroupand heavy subgroup from MCT group, respectively; but the incidence of complications was 26.87% and 18.82% in extra- heavy subgroup and heavy subgroup from CCT group; significant differences were noted (P<0.05). GOS showed that the mortality rates (GOS score: 1) for the extra-heavy subgroup and heavy subgroup from MCT group were 53.08% and 17.88%, while those for CCT group were 67.16% and 26.80%, with significant differences (P<0.05). The severe disability rates (GOS scores: 2-3) for the extra-heavy subgroup and heavy subgroup from MCT group were 21.12% and 13.48%, while those for CCT group were 26.87% and 20.72%, with significant differences (P<0.05). The good recovery rates (GOS scores: 4-5) for the extra-heavy subgroup and heavy subgroup from MCT group were 25.12% and 68.64%, respectively, while those for CCT group were 5.97% and 52.47%, with significant differences (P<0.05). Conclusion The operation of MCT bedside scanning is simple, safe and reliable in the NICU, enjoying good clinical effects as compared with CCT scanning. Key words: Craniocerebral injury; Mobile CT; Secondary cerebral injury; Glasgow coma scale; Glasgow outcome scale