Abstract

Background and Aims : Experimental and clinical evidence supports the critical role of inflammation in atherosclerosis, independent of the cholesterol level. The purpose of this study is to evaluate the effect of short-term treatment with minocycline, a tetracycline antibiotic, that has been shown to possess anti-inflammatory properties, on survival, inflammation, oxidative stress and monocyte population in a diet-induced myocardial infarction mouse model.

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