Abstract
The effect of parenteral administration of melatonin on the levels of pituitary LH activity of castrated and castrated, testosterone- treated male rats was studied. The possible direct effect of melatonin on the accessory sex glands, structures well recognized to be under the control of androgenic hormones, was also investigated. Melatonin caused a significant decrease in the weight of the adenohypophyses in castrated rats and also in 1 of the 2 groups of castrated, testosterone-treated male rats. Melatonin also induced significant decreases in ventral prostate weights in both groups of castrated, testosterone-treated rats. Pituitary LH concentration was not significantly affected in any group. Pituitary LH content appeared lower in all groups treated with melatonin. These results suggest a possible direct effect of melatonin on the ventral prostates, which in some way modifies the stimulatory effect of testosterone on these structures.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
