Abstract

AbstractNuclear Magnetic Resonance (NMR) technique is a convenient method to monitor magnetic nanoparticles in different biomedical applications and observe changes induced by the particles. To better understand the specifics of the magnetic resonance and spin relaxation in the systems with magnetic nanoparticles, the NMR spectra and magnetization dynamics of the host protons are studied in the model systems of different viscosity and some biological systems in the presence of magnetic nanoparticles. The results confirmed that nanoparticles affect the proton relaxation kinetics of liquid solutions, changing the relaxation time (T1) significantly, whereas in systems of high viscosity the relaxation times are unchanged. The kinetics in intermediate systems is multi-exponential. A complicated picture is observed in biological systems, demonstrating contributions of liquid-like and solid-like behavior.

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