Effects of Lycopene on Sperm Parameter in Healthy Male: A Review

Abstract

Infertility is an ability of couple to have a baby after one year of unprotected intercourse affects 48.5million couple in worldwide. Out one of four couple are affected by infertility. A minimum 30 million men world-wide are infertile and male factor are responsible for approximately 20-30% in all infertile cases. It is now understood that oxidative stress plays a significant role in the aetiology of male infertility. Reactive oxygen species (ROS) in excess lead to an oxidative stress condition that reduces sperm viability and motility by causing DNA damage, apoptosis, and lipid peroxidation of the sperm membrane. Increased ROS levels are a crucial role in idiopathic male factor infertility, which is a disease that is becoming more prevalent in society today. Due to its antioxidant qualities, lycopene, the most effective singlet oxygen quencher of all carotenoids, may be used to treat male infertility. Lycopene may minimise the occurrence of oxidative stress and, consequently, the harm that would otherwise be done to spermatozoa by interacting with and neutralising free radicals. We have analysed data from a number of sources and provided information regarding lycopene and its impact on male infertility in this review paper. The focus of this review is on how lycopene affects sperm parameters in healthy men.