Abstract
Cardiac output, arterial, central venous and left ventricular pressures and systolic time intervals were measured in patients with uncomplicated acute myocardial infarction during room air breathing and administration of oxygen at 6 L/min. With oxygen cardiac output decreased and arterial pressure increased. These changes were of small magnitude. Measurement of left ventricular pressures, stroke work, and the ratio of pre-ejection period to left ventricular ejection time failed to show evidence of impaired ventricular performance resulting from oxygen administration. Blood gas measurements revealed a high incidence of hypoxemia which was easily corrected by administration of low-flow oxygen. From these data we conclude that low-flow oxygen does not significantly impair the hemodynamic status or left ventricular performance of patients with uncomplicated acute myocardial infarction. Since hypoxemia is often present, low-flow oxygen should be used routinely.
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