Abstract
Plinia cauliflora (Mart.) Kausel, popularly known as jabuticaba, is rich in polyphenols. Phenolic compounds exhibit several biological properties, which reflect on biomarkers such as biochemical parameters. In the present study, we evaluated the plasmatic levels of glucose, total cholesterol, HDL-cholesterol, triglycerides, and uric acid of Chinese hamsters fed for 45 days with a regular diet or cholesterol-enriched diet supplemented with a liquid extract obtained from P. cauliflora fruits residues standardized in ellagic acid and total phenolic compounds. The results showed that the concentrated extract obtained from jabuticaba residues increased the glycemia of animals fed with a regular diet and reduced the plasmatic uric acid levels of animals fed with a cholesterol-enriched diet. Since hyperuricemia is considered to be a significant risk factor of metabolic disorders and the principal pathological basis of gout, the liquid extract from P. cauliflora fruits residues would be a promising candidate as a novel hypouricaemic agent for further investigation.
Highlights
Jabuticaba - Plinia cauliflora (Mart.) Kausel - is a fruit that belongs to the Myrtaceae family, occurring mainly in Brazil’s southeastern in some biomes and is typical of the Brazilian Cerrado
Liquid extract from Plinia cauliflora fruits residues on biochemical parameters collected by cardiac puncture into EDTA flasks
The concentrated liquid extract from jabuticaba residues increased the glycemia (27.5%) of Chinese hamsters with a regular diet (Figure 1), which could be explained by the presence of molecules that arrived from the fermentation process, such as soluble sugars (Silva et al, 2008)
Summary
Jabuticaba - Plinia cauliflora (Mart.) Kausel - is a fruit that belongs to the Myrtaceae family, occurring mainly in Brazil’s southeastern in some biomes and is typical of the Brazilian Cerrado. Jabuticaba hydroalcoholic extract presented a good performance in a spray-drying process to obtain a powder standardized in ellagic acid and total phenolic compounds (Borges et al, 2015). According to Andrade et al (2015), the concentrated liquid extract from jabuticaba residues presented in vitro activity to reduce the vascular tension and the blood pressure of isolated aortas from rats. This result revealed the great potential for the reuse of this raw material due to its biological properties. The present study’s objective was to evaluate the effects of concentrated liquid extract obtained from jabuticaba residues on biochemical parameters of diet-induced hypercholesterolemic Chinese hamsters
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