Abstract
Perioperative depression symptom is a common perioperative complication, but limited interventions could relieve such depressive condition effectively. Ketamine could alleviate the depressive symptoms in patients with treatment-resistant depression. These findings provide clinical evidence for the application of ketamine on patients with perioperative depression. This article reviewed researches for the assessment and treatment about perioperative depressive symptoms. This review focused on the feasibility, safety and related biomarkers of administration ketamine for depressive symptoms. Key words: Ketamine; Perioperative; Depressive state
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