Abstract
The endogenous excitatory amino acids aspartate and glutamate are considered the most likely candidates as putative transmitters in the mammalian CNS. They act on one or more receptors. On the basis of electrophysiological studies, using mainly spinal cord preparations, three classes of excitatory amino acid receptors have been proposed: NMDA, quisqualate and kainate (Watkins and Evans, 1981).
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