Abstract
Chromosome aberrations, sister chromatid exchanges and micronuclei were studied in irradiated and unirradiated peripheral blood lymphocytes of smokers and nonsmokers. No effect of smoking could be observed in the number of chromosome aberrations, either in the irradiated or nonirradiated samples. Smokers had significantly elevated SCE values in the unirradiated samples, but the difference in SCE frequencies between smokers and nonsmokers in the irradiated series was not significant. The mean frequency of micronuclei in smokers was significantly higher than in nonsmokers. After irradiation the mean difference in micronuclei frequencies between smokers and nonsmokers was greater than the difference between the unirradiated samples of the two groups.
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