Abstract
In this study, the use of ionic liquids as additives in the separation of 2-chlorophenol and 2,4,6-trichlorophenol in reversed-phase high-performance liquid chromatography is reported. The ionic liquids used were 1-butyl-3-methylimidazolium tetrafluoroborate, 1-ethyl-3-methylimidazolium tetrafluoroborate, 1-ethyl-3-methylimidazolium methylsulfate ([EMIm][MS]), and 1-octyl-3-methylimidazolium methylsulfate ([OMIm][MS]), because of their high hydrophobicity and good solvating properties. The effects of the ionic liquid on retention factor and resolution, and the change of detector response using the different ionic liquids were studied. Separation with the [MS] anion ionic liquid in the eluent resulted in better resolution than with the [BF4] anion ionic liquid. The best result was achieved using 3.0 mM/L of [OMIm][MS] and 1.0 mM/L [EMIm][MS] as mobile phase additives.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
