Abstract
Abstract: The effect of insulin (0.1 U/ml) on glucose metabolism was studied in bovine mesenteric arteries and rabbit colon smooth muscle. In both tissues the glucose uptake was enhanced by insulin after an incubation period of 180 min. and at a glucose concentration of 5.6 mM. Insulin also augmented the incorporation of glucose‐14C into glycogen as well as the glycogen content and the lactate elimination. Glycogen synthetase I activity was increased by insulin. The total glycogen synthetase, phosphorylase a or total phosphorylase activities were not affected. The effects of insulin on the glucose metabolism in bovine mesenteric arteries and rabbit colon smooth muscle were qualitatively similar to those in rat skeletal muscle but the effects were less pronounced and appeared later.
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