Abstract
home Acta Veterinaria Brno Journal of the University of Veterinary Sciences Brno, Czech Republic Search:
Highlights
The infectious bursal disease virus (IBDV) belongs to the family Birnaviridae (Brown 1986), and it consists of two segments of double-stranded RNA (Jackwood et al 1984)
The chickens were vaccinated at 14 days of age, and titres of post-vaccination antibodies, group positivity and the degree of damage to the bursa of Fabricius were assessed at day 10 and 17 post vaccination
The most frequently used index of the vaccination virus virulence is the relative weight of the FB (Mazariegos et al 1990)
Summary
Juranová: Effects of Infectious Bursal Disease Vaccination Strains on the Immune System of Leghorn Chickens. Levels of post-vaccination antibodies against infectious bursal disease were monitored by the ELISA test in seven experiments with Leghorn chickens free of maternal antibodies. Effects of vaccination strains on the chickens’ immune system were assessed using the bursa of Fabricius index, and a statistical comparison with results from a control group was made. The most virulent vaccines E and F demonstrated an almost 100% positivity, high post-vaccination antibodies titres and, as expected, statistically significant (p < 0.01) bursal atrophy. Infectious bursal disease (IBD) is an acute and highly contagious viral disease affecting young chickens and is characterized by massive damage to the bursa of Fabricius (FB) and by immunosuppression (Lukert et al 1997). While some infected chickens will not even show any clinical symptoms of the disease, other chickens may die: in specific pathogen free (SPF) chickens, IBD mortality ranges between 30% and 70% (Nunoya et al 1992)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
