Abstract

Effects of individual fractions of the liquor preparation from drug addicts, eluted from filters after liquor adsorption session, on rat behavior in an elevated plus-maze was analyzed. Fraction I activated and fraction IV inhibited orientation and exploratory activity and increased anxiety of experimental animals. Effects of fraction IV coincided with the effect of total preparation on rat behavior in an elevated plus-maze, which indicates that this fraction contains substances actively accumulating in the liquor of drug addicts and partially responsible for functional changes observed during abstinence.

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