Abstract
Effects of Increasing Dietary Alpha-Linolenic Acids on Nursery Pig Growth Performance and Response to Immune Challenge
Highlights
IntroductionOmega-3 fatty acids (alpha linolenic acid) have been found to improve immune function and lessen the febrile response to immune system activation
Omega-3 fatty acids have been found to improve immune function and lessen the febrile response to immune system activation
On d 25, two pigs per pen were injected with 20 μg of Eschrichia coli (E. coli) lipopolysaccharide (LPS) per kg BW and one pig per pen was injected with 2 mL of saline to serve as a control
Summary
Omega-3 fatty acids (alpha linolenic acid) have been found to improve immune function and lessen the febrile response to immune system activation. The mode of action is thought to be through a decrease in the omega-6:3 fatty acid ratio. Research has demonstrated that lowering the ratio of omega-6:3 to a range of 3:1 or 5:1 instead of the normal 10:1 or 20:1 observed in typical swine diets, increases incorporation of omega-3 fatty acids into cell membranes to make it available to be utilized during an immune challenge.[2]. Our hypothesis was that by changing the omega-6:3 ratio using O3 Trial Feed, we would observe an improved responsiveness to an immune challenge. The objective of this study was to determine the effectiveness of O3 Trial Feed, a source of omega-3 fatty acids, on nursery pig performance and response to an LPS immune challenge
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