Abstract
Insulin growth factor 1 (IGF-1) is an important growth stimulating factor, with insulin-like action, which can promote cell growth, development, participate in a variety of physiological and pathological processes. IGF-1 is involved in the development of metabolic diseases such as short stature, obesity, type 2 diabetes mellitus, metabolic bone disease and so on. At the same time, the effects of IGF-1 includes promoting the growth and development of children′s porosis bone, promoting the decomposition of lipids, reflecting the severity of insulin resistance, improving insulin sensitivity, increasing bone density, and preventing osteoporosis. Key words: Insulin growth factor-1; Metabolic diseases; Diabetes mellitus
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