Abstract
1. 1. The effects which experimental hypothermia induces on rabbit and rat biliary secretion have been investigated. 2. 2. In both species we have found a drastic reduction in bile-flow and in bile salt output and an increase in bile-salt concentration. 3. 3. Hypothermia induces a substantial decrease of bile salt independent fraction (BSIF) in both rabbit (80%) and rat (70%) which we believe may be due to a loss of activity of Na +, K +-activated ATPase. 4. 4. Rewarming is not able to reverse the negative effect that hypothermia has on rabbit bile flow.
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