Abstract
Hypophysectomy caused enophthalmos in the crucian carp ( Carussius carassius L.), i.e. it decreased the bulk of orbital contents. Thyroxine was truly exophthalmogenie, i.e. it increased the bulk of orbital contents in hypophysectomized as well as unoperated fish. d - and l -thyroxine did not differ as to exophthalmogenic effect in intact fish. The content of glycosaminoglycans in the retrobulbar connective tissue was not changed after hypophysectomy, although the ratio of glucosaminoglycans to galactosaminoglycans decreased. Thyroxine treatment caused a slight decrease in the glycosaminoglycans, probably due to a decrease in hyaluronic acid. The glycoproteins probably decreased after hypophysectomy but increased after thyroxine administration. The content of hydroxyproline did not change.
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