Abstract
Untreated anemia can caused significant cardiac and kidney damage. The aim of this study was to investigate the efficiency of anemia and hyperglycemia treatment in type 2 diabetes and their impact on kidney and heart impairment. The study is clinical retrospective and prospective and it was conducted in Clinic of Endocrinology, Diabetes Mellitus and Metabolic Diseases, University Clinical Center of Sarajevo. Prior to the study all patients were taking oral hypoglycemic drugs included sulfonylureas and biguanides. These subjects were put on 2 times daily fix mix insulin and biguanides after lunch. Each day, subjects received Iron tab 1 x 100 mg/ day, and C vitamin 1 x 100 mg/day. The results of our study are showing that effective treatment of glycaemia and anemia in patients with diabetes, reduces blood pressure, urine albumin secretion and pulse rate, diminishing cardiovascular damage and improving kidney function.
Highlights
People with diabetes have suffered from anemia for a number of years before receiving treatment
Patients with chronic kidney disease and anemia experience an increased risk of stroke compared to patients without chronic kidney disease
Anemia therapy in patients with heart failure may reduce the risk of subsequent hospitalization, and anemia therapy in patients with chronic kidney disease not on dialysis may reduce the risk of progression of chronic kidney disease (, )
Summary
People with diabetes have suffered from anemia for a number of years before receiving treatment. Heart has to work harder to pump blood around the body due to the limited amount of oxygen – carrying hemoglobin through the blood stream, what can deteriorate a high risk of coronary heart disease in people with type diabetes ( , , , ). Patients with chronic kidney disease and anemia experience an increased risk of stroke compared to patients without chronic kidney disease. Anemia therapy in patients with heart failure may reduce the risk of subsequent hospitalization, and anemia therapy in patients with chronic kidney disease not on dialysis may reduce the risk of progression of chronic kidney disease ( , ).
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