Effects of Hyper- and Hypothermia on Hemodynamic Parameters in People of Different Age Groups: Meta-Analysis

Abstract

Age-related changes in thermoregulation occur due to the deterioration of the adaptive capacity of the cardiovascular system caused by remodeling of the vascular wall and myocardium, capillary density reduction, changes in the synthesis and clearance of neurotransmitters and vasoactive substances, as well as the inhibition of the vegetative mechanisms of hemodynamic parameters regulation. A common way to simulate hyper- and hypothermal conditions is to use a suit with tubes to fill with water at different temperatures. The purpose of this work is to conduct a meta-analysis of the hemodynamic parameters shifts when modeling hyper- and hypothermia using such a suit in people of different age groups. As a result of the meta-analysis, it was found that heating the whole body is accompanied by a decrease in blood pressure (BP) and an increase in heart rate (HR). The reaction of hemodynamic parameters to hyperthermia does not significantly change with aging. Cooling of the whole body is accompanied by an increase in BP without changing the HR. In hypothermia, the amplitude of the elevation of the systolic BP is greater in older people.