Effects of high-intensity interval training on glucose homeostasis and cardiac function in patients with type 2 diabetes mellitus

Abstract

Objective To investigate the effect of high-intensity interval training on glucose homeostasis and cardiac function in patients with type 2 diabetes mellitus. Methods A total of 56 inpatients in Endocrine Department of the Fourth Affiliated Hospital of Harbin Medical University from March 2017 to August 2018 were randomly divided by convenient sampling method into an intervention group and a control group, with 28 inpatients in each. The inpatients in the control group received the standardized care process while the intervention group would further received the high intensity interval training. The homeostasis model assessment insulin resistance (HOMA-IR) , ejection fractions (EF) and cardiac output (CO) were compared before and after the intervention. Results After intervention, HOMA-IR in the intervention group was (6.32±1.65) %, lower than that in the control group (7.22±1.40) %, the difference between the two groups was statistically significant (t=2.20, P=0.03) . After intervention, there was no significant difference in EF and CO between the two groups (P>0.05) . Conclusions The high intensity interval training can improve the level of glucose homeostasis in patients with type 2 diabetes, but more evidence is needed for the effect on heart function in the future. Key words: Diabetes mellitus, type 2; High intensity interval training; Glucose homeostasis; Cardiac function