Abstract

It is well known that growth hormone (GH) is important in the regulation of longitudinal bone growth (1; 2). Its role in the regulation of bone metabolism in man has not been understood until recently (1). Bone remodeling is regulated by a balance between bone resorption and bone formation. Recent studies, which demonstrate that GH exerts potent effects on bone remodeling, will be discussed in this chapter. Finally a hypothetical model for the mechanism of action of GH in the regulation of bone remodeling and bone mass will be presented.

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