Abstract

Summary o 1. Behavioural differences between (i) the strains DBA/2J, C57BL/6J, and their F 1 hybrids, and (ii) homozygous and heterozygous short-ear ( se ) animals, were examined. For this purpose more than thirty stereotyped behavioural components performed by single male house mice and by pairs of males when placed into an observation cage, and avoidance behaviour in a shock escape box were taken into consideration. 2. Many strain differences not described previously were established; others generally confirmed earlier findings. Strain DBA/2J is mainly characterized by low scores for various locomotory and exploratory activities, and strain C57BL/6J by low values for feeding behaviour, defecation, grooming, and aggressiveness. There was no clear-cut difference in active avoidance learning between these strains. The B6D2F 1 hybrid showed evidence of hybrid vigour, they rated high particularly with regard to leaning postures, climbing, manipulation of bedding material, and learning performance. 3. The se locus was found to influence avoidance behaviour; mutants did less well than nonmutants. No effect upon the frequencies of fixed action patterns or upon general activity was observed.

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