Abstract
The normal midgut consisted of an epithelial layer, a thin basement membrane, an inner circular muscle coat, and outer bundles of longitudinal muscles. The major cytological damage associated with radiation exposure was displayed by the midgut epithelium. Damage ranged from moderate cell disruption 4 days after treatment with 5 krads to almost complete histolysis following 50 krads. The regenerative cells that renew the epithelial lining of the midgut were particularly sensitive to radiation damage resulting in an inability to replace the midgut epithelium.
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