Effects of F-strain Mycoplasma gallisepticum inoculation at twelve weeks of age on the blood characteristics of commercial egg laying hens

Abstract

In two trials, the effects of an F-strain Mycoplasma gallisepticum (FMG) inoculation at 12 wk of age on the blood characteristics of commercial Single Combed White Leghorn laying hens were investigated throughout lay. Variables measured in both trials were whole blood hematocrit, plasma protein (PP), and serum cholesterol, triglycerides (ST), and calcium. In both trials, hematocrit at 20 wk of age was significantly increased in birds inoculated with FMG. In trial 1, ST and PP were significantly increased at 22 wk of age by FMG, while ST and PP were significantly decreased in FMG-inoculated birds at wk 54 and 52, respectively. When combined with the establishment of an FMG infection, the initial weeks of egg production become particularly stressful to the bird. Increases in these independent blood parameters between 8 and 10 wk postchallenge are suggestive of compensatory responses in these birds to an FMG challenge. Postpeak decreases in both ST (54 wk) and PP (52 wk) in FMG-infected birds may be the result of a more chronic effect of FMG on lipid and protein synthesis in the liver. These data are the first to suggest that alterations in egg production in response to FMG-infection in commercial layers, as noted in a previous report, may be associated with changes in hematocrit. However, because ST and PP were not affected by FMG in both trials, the responses of these blood parameters to FMG-infection may be inconsistent among flocks.