Abstract
Abstract Thirty adult albino male rats, Sprague Dawley strain were randomly classified into fife groups (6 rats each). The first group kept as normal control fed standard diet only. The other fourth groups fed on basal diet containing 2% (W/W) arginine to induce renal failure for two weeks reclassified into positive control, pan bread fortified with 5% asparagus, pan bread fortified with 10% asparagus, and pan bread fortified with 15% asparagus groups. This study aimed to investigate effect of asparagus with fortified pan bread on the levels of some biochemical parameters as kidneys function, liver function and lipid profile of chronic renal failure in rats. The present study investigated the effect of asparagus fortified pan bread 5%, 10% and 15% ASP G. The results revealed significant decrease in uric acid, creatinine and urea nitrogen. The results revealed that decrease significant in AST, ALT and ALP levels compared with the positive control group. The results revealed that, the positive control group increase significant in TC, TG, LDL–c and VLDL–C. while showed significant decrease in serum glutathione, catalase and SOD. Pathological results of organs showed damage in them. In contrary, feeding rats on died containing asparagus especially at high level (10%) revealed marked improvement of these parameters and histopathological.
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