Abstract
Along with clinical and endocrine modifications ovarian morphology continues to be the basis for the diagnosis of polycystic ovaries syndrome (PCOS). Androgenic effects on the ovaries may be caused either by testosterone or by dihydrotestosterone. The enzyme that catalizes the transformation from testosterone to DHT is the 5-a-reductase which is present in the follicles stroma and luteal bodies of women’s ovaries. Treatment with inhibitors of the 5-a-reductase blocks the transformation from testosterone to DHT. The objective of the study was to evaluate ultrasonographic differences in the ovaries of women with this syndrome after treatment with finasteride an inhibitor of 5-a-reductase. (excerpt)
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