Abstract
Far infrared light has been used in many medical procedures. However, the detailed biological mechanisms of infrared light’s effects have not yet been elucidated. Many researchers have pointed out the thermal effects of treatments such as infrared saunas, which are known to increase blood flow. Alzheimer’s disease (AD) is associated with gradual decreases in brain blood flow and resulting dementia. In this study, we attempted to clarify the beneficial effects of far infrared light using the 5xFAD mouse, a transgenic model of AD. We exposed 5xFAD mice to far infrared light for 5 months. Among the far infrared-exposed AD mice, body weights were significantly decreased, and the levels of nerve growth factor and brain-derived neurotrophic factor protein were significantly increased in selected brain areas (compared to those in non-irradiated AD mice). However, cognition and motor function (as assessed by Morris water maze and Rota Rod tests, respectively) did not differ significantly between the irradiated and non-irradiated AD mouse groups. These results indicated that exposure to far infrared light may have beneficial biological effects in AD mice. However, the experimental schedule and methods may need to be modified to obtain clearer results.
Highlights
The electromagnetic wave, which was discovered by Heinrich Rudolf Hertz in 1887, is a wave function that proceeds in a specific direction while crossing electric and magnetic fields
To clarify the biological effects of Far IR (FIR) light, we measured the body weights of control and Alzheimer’s disease (AD) mice that were housed with a fabric that either emitted FIR light or with one that did not
The relative body weight gain of AD mice was nominally attenuated in animals housed with the fabric that generates FIR light (Fig 2)
Summary
The electromagnetic wave, which was discovered by Heinrich Rudolf Hertz in 1887, is a wave function that proceeds in a specific direction while crossing electric and magnetic fields. Electromagnetic waves have many characteristics such as reflection, transparency, absorption, refraction, and scattering. Examples of electromagnetic wave applications include the clinical use of X-ray imaging to visualize internal organs, and the heating of objects by the reflection of infrared (IR) waves [1]. Effects of far infrared light on AD mice electromagnetic wave-based technologies. The use of electromagnetic waves is essential to the comforts of our modern daily life
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