Abstract
In this study, we assessed the effect of rehabilitation exercise after percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD). We performed a meta-analysis to determine the effects of exercise in patients after PCI. The Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, the Embase database, China National Knowledge Internet (CNKI), China Biology Medicine (CBM), and the Wanfang Database were searched for randomized controlled trials (RCTs). The key words used for the searches were PCI, exercise, walking, jogging, Tai Chi, and yoga. Six studies with 682 patients met our inclusion criteria; we chose the primary endpoint events of cardiac death, recurrence of myocardial infarction (MI), repeated PCI, coronary artery bypass grafting (CABG), and restenosis, and the secondary endpoint measures included recurrent angina, treadmill exercise (total exercise time, ST-segment decline, angina, and maximum exercise tolerance). The results showed that exercise was not clearly associated with reductions in cardiac death, recurrence of MI, repeated PCI, CABG, or restenosis. However, the exercise group exhibited greater improvements in recurrent angina, total exercise time, ST-segment decline, angina, and maximum exercise tolerance than did the control group. Future studies need to expand the sample size and improve the quality of reporting of RCTs.
Highlights
Studies have shown that exercise has beneficial effects on human health, such as reducing the risk of dementia[15], providing protection against metabolic disorders[16], and improving quality of life[17]
Additional studies were excluded because they were meta-analyses or case studies, data for the exercise group were not available, the outcomes of interest were not reported, or dichotomous data that were very important for our statistical analysis were not provided
4.3 Repeated percutaneous coronary intervention (PCI) 4.4 Coronary artery bypass grafting (CABG) 4.5 Restenosis. This is the first meta-analysis about the effects of exercise-based cardiac rehabilitation for Coronary heart disease (CHD) patients who have undergone PCI
Summary
Studies have shown that exercise has beneficial effects on human health, such as reducing the risk of dementia[15], providing protection against metabolic disorders[16], and improving quality of life[17]. Exercise-based cardiac rehabilitation is aimed at improving the health and outcomes of people after PCI. Some studies have demonstrated that exercise is good for rehabilitation and recurrent symptoms after PCI. Reports of advantages that translate to measurable clinical outcomes following PCI are few. This systematic review aims to answer the following questions: (1) does exercise affect the primary endpoint events of cardiac death, recurrence of MI, repeated PCI, CABG, and restenosis after PCI? (2) Is exercise an effective method for improving secondary endpoint measures, such as quality of life, physical function, and symptoms, after PCI? This systematic review aims to answer the following questions: (1) does exercise affect the primary endpoint events of cardiac death, recurrence of MI, repeated PCI, CABG, and restenosis after PCI? (2) Is exercise an effective method for improving secondary endpoint measures, such as quality of life, physical function, and symptoms, after PCI?
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