Abstract
The effects of sex, castration and estrogen treatment of castrated rats subjected to starvation-refeeding were studied. Food intakes, liver lipid levels and the activities of glucose 6-phosphate dehydrogenase and malic enzyme in ad libitum-fed, starved and starved-refed rats were determined. Sex differences observed in the intact ad libitum-fed rats could be explained in part by the differences in estrogen levels. Sex differences were obliterated in the starved-refed intact rats but were observed when castrated female starved-refed rats were compared to castrated male starved-refed rats. These differences could not be erased with the administration of estrogen. Estrogen significantly reduced food intake of castrated rats. Results of this study suggest that the characteristically higher liver lipid level and enzyme activity in the female, compared to the male, may reflect the female’s tendency to undereat when circulating estrogen levels are high and to compensate (by overeating) for this undereating when estrogen levels are low.starvation-refeeding sex differences estrogen lipogenesis
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
