Abstract
Polymyxin B immobilized fiber (PMX-20R: Toray Industries, Inc) has been developed in Japan for direct removal of endotoxin. Hanasawa et al [1] reported the use of a PMX-20R column for treating endotoxemia in animal and clinical studies. Polymyxin B was chemically fixed onto polystyrene fiber to remove endotoxin by direct hemoperfusion. We used PMX-20R to treat septic shock patients who had developed complicated multiple organ failure.
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