Abstract
Effects of Electrode Placement and Measurement Time on Electrochemical Signal of Redox Species Flowing through Porous Material
Highlights
Point-of-care testing (POCT) is an easy, fast, and low-cost diagnostic method conducted at the bedside, near the patient, and on-site.[1]
We studied the construction of an electrochemical immunochromatography platform as one of the point-of-care testing devices from both experimental and theoretical aspects
We investigated the effect of the layout of the electrodes of the electrochemical detector on the electrochemical measurement
Summary
Point-of-care testing (POCT) is an easy, fast, and low-cost diagnostic method conducted at the bedside, near the patient, and on-site.[1]. Martinez et al introduced a microfluidic paperbased analytical device (μPAD) in which paper is used as the substrate for the immunoassay.[4] They demonstrated various biosensing techniques, for example, paper-based enzyme-linked immunosorbent assay (ELISA) and paper-based electrochemical glucose sensing, which can be accomplished with the commercialized glucose sensor.[5,6] μPADs have attracted attention for human diagnosis and for use in agricultural fields and environmental measurement because of their very low cost measurement and easy fabrication methods. We demonstrated the electrochemical measurement of redox species flowing through a porous material using two types of electrochemical detectors that have different placements of each electrode. We investigated the relationship between the electrochemical signal and the elapsed time after the sample solution was applied to the porous material
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