Abstract
An effort was made to determine whether the changes in activity levels of rats that received electroconvulsive shock (ECS) after either cold stress or foot shock could be related to changes in serotonin, norepinephrine, or dopamine levels in various parts of the brain. The brain regions sampled were the frontal pole, the caudate nucleus, and the remainder. There were some changes in the levels of these amines as a consequence of ECS treatment but the more significant changes were related to the type of stress the rats had been subjected to before ECS treatment. No clear relationships between changes in the levels of these amines in the brain and the reported changes in activity levels following ECS could be identified.
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