Abstract
Following vibrissae removal in early ontogenesis from P1 (post-natal day 1) to P30, three-month old rats were trained to run for food in an 8-arm radial maze. Training started at the age of three months. Adult rats demonstrated ability to perform the behavioral task; however, their performance was not as good as in the control group. Our findings revealed the differences in the rats exploratory strategy and key behavioral tactics of entering the maze arms at a certain angle. The results show that active vibrissae sensing plays an important role in shaping rat behavioral tactics during spatial learning in the 8-arm radial maze.
Highlights
Studies into sensory deprivation in early ontogenesis yield extensive information concerning the formation of functional systems underlying adaptive behaviors (Raevskii et al, 1997).Numerous investigations have been made of the sensory deprivation effects on the developing organism
Assessment of the number of correct entries made by the rats before the first erroneous trial occurred (Fig. 2) showed that despite a positive performance progress that occurred in both groups with training, this parameter related to the working memory is considerably higher in the control rats
Several studies have indicated the important role played by active vibrissal sensing from an early age in locomotion and exploratory behavior (Arkley, Grant, Mitchinson, and Prescott, 2014; Grant, Mitchinson, and Prescott, 2012; Shishelova, Aliev, and Raevski, 2016)
Summary
Numerous investigations have been made of the sensory deprivation effects on the developing organism. Overviews in the literature report various behavioral models used to investigate effects of various types of sensory deprivation on behavior during early development (Korneeva, Aleksandrov, Golubeva, and Raevskii, 2010; Shishelova, 2006; Shishelova and Raevskii, 2010; Shishelova, Aliev, and Raevskii, 2016). Data providing evidence for the consequences of early sensory deprivation for memory and learning are limited (Grigoryan, Hodges, and Gray, 2005; Papaioannou, Brigham, and Krieger, 2013; Symons and Tees, 1990). An assessment was made of the consequences of selective early sensory deprivation on the spatial behavior of the adult rat. The aim of this study was to investigate the behavioral effects of early bilateral vibrissal removal (trimming) on spatial learning in adult rats
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