Abstract
SUMMARYThe effects of selection for increased or decreased body weight in mice, at 5 or 10 weeks of age, on the fibre number, fibre diameter and weight of the m. sternomastoideus and m. anterior tibialis muscles were studied. Unselected control mice were also included. Significant effects were detected in the case of each of the traits. However, the magnitude of any particular correlated response to selection varied between muscles and between selection ages in an unsystematic fashion. Most of the changes in muscle weight resulting from selection were attributable to positively correlated changes in fibre number but they were also accompanied by changes in fibre diameter in some cases.The correlated responses described indicate the difficulty of predicting how selection for body weight changes will influence cellular structure of any given muscle.Phenotypic correlations between muscle fibre number and diameter were essentially zero. The phenotypic correlations between muscle weight and fibre number and fibre diameter were positive.Sex had no effect on fibre number but had an effect on fibre diameter which depended on the particular muscle and the age of the animal.
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