Abstract

Dioxin is still long persistent in environment. The effect of Dioxin on thyroid function is inconsistent. Da Nang and Bien Hoa airbases have been hot spots for persistent contamination since 1961. Inhabitant living around these sites has been exposed to dioxin for a long time. Serum dioxin level of people was much higher than those in other sites. This study evaluates serum dioxin level using DR CALUX and thyroid function including T3, T4, FT3, FT4, TSH measurement. T3 level was found association with serum dioxin level. There were not any relation between T4, FT3, FT4 and TSH and dioxin level.

Highlights

  • Dioxins [polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs)] are highly toxic environmental contaminants, which are lipophilic and resistant to biodegradation

  • Da Nang and Bien Hoa airbases were considered as hot spots of dioxin contamination in Vietnam

  • Tai et al [4] recently showed that levels of PCDDs/Fs in the breast milk of mothers residing near hot spots were threefold to fourfold higher than those in the breast milk of mothers living in unsprayed areas, and that infant daily dioxin intake (DDI) of Vietnamese infant in hot spots were estimated to be twofold to threefold higher than the recently documented values in US and Japanese infants [4]

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Summary

Introduction

Dioxins [polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs)] are highly toxic environmental contaminants, which are lipophilic and resistant to biodegradation. We want to clarify the effects of dioxin exposure on thyroid function of general populations living in Da Nang and Bien Hoa airbases. Statistical analysis: we used median of Dioxin level (69.16 BEQ) as cut off to divide the subjects into two groups, high category and low category.

Results
Conclusion
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