Abstract
Addition of Me 2S to a 1:2 CuI/BuLi mixture in toluene promotes 1,4- over 1,2-addition in reactions with a representative selection of α,β-unsaturated ketones. Unlike similar reactions studied with dialkyl ethers, the effect of Me 2S is not related to the amount of lithium salts in the reaction medium. The results are related to current mechanistic theories of organocuprate reactions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.