Abstract
For transillumination imaging of animal tissues, we have attempted to suppress the scattering effect in a turbid medium using the time-reversal principle of phase-conjugate light. We constructed a digital phase-conjugate system to enable intensity modulation and phase modulation. Using this system, we clarified the effectiveness of the intensity information for restoration of the original light distribution through a turbid medium. By varying the scattering coefficient of the medium, we clarified the limit of time-reversal ability with intensity information of the phase-conjugate light. Experiment results demonstrated the applicability of the proposed technique to animal tissue.
Highlights
The use of light in many biomedical applications has progressed rapidly recently
We investigated the influence of the intensity information of the phaseconjugate light on suppression of the scattering effect in optical transillumination imaging
With a view toward the suppression of scattering effect in optical transillumination imaging of animal tissues, we examined the effect of intensity modulation for the time-reversal function of digital phase-conjugate light
Summary
The use of light in many biomedical applications has progressed rapidly recently. Benefits of using light include its non-invasiveness to animal tissue and its capability of functional imaging. To enhance biomedical applications, we investigated the scattering suppression effects of phaseconjugate light with a non-focusing system. In conventional bioimaging using digital phase-conjugate system [1,2,7,8,16], phase-conjugate light is generated with a single SLM and CMOS camera [17,18] In such a system, phase modulation is emphasized. If correct digital phase-conjugate light is obtainable, the scattering effect in transillumination imaging can be suppressed effectively by the time-reversal principle. We investigated the influence of the intensity component of digital phase-conjugate light on suppression of the scattering effect in transillumination imaging, and verified its importance. We strove to clarify the limit of the scattering suppression capability of this technique with a non-focusing system
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