Effects of different fluid therapy protocols on postoperative nausea and vomiting in pediatric patients undergoing ambulatory surgery

Abstract

Objective To evaluate the effects of different fluid therapy protocols on postoperative nausea and vomiting (PONV) in pediatric patients undergoing ambulatory surgery. Methods A total of 160 pediatric patients, of American Society of Anesthesiologists physical status Ⅰ or Ⅱ, aged 3-7 yr, weighing 14-24 kg, with body mass index <30 kg/m2, undergoing elective lower abdominal ambulatory surgery, were randomized into Ⅰ and Ⅱ groups (n=80 each) using a random number table method.Lactated Ringer′s solution 10 ml·kg-1·h-1 and 30 ml·kg-1·h-1 were intravenously infused in group Ⅰand group Ⅱ, respectively.Ibuprofen 20 mg/kg was given orally after operation to maintain Face Legs Activity Cry Consolability score ≤4.The development of PONV and thirst and requirement for antiemetics was recorded within 24 h postoperatively.The time of first PONV, time of first thirst and score for satisfaction of family members were also recorded. Results Compared with group Ⅰ, the incidence of PONV and thirst was significantly decreased, the time of first requirement for antiemetics and time of first thirst were prolonged, and the score for satisfaction of family members was increased (P 0.05). Conclusion Intravenously infusing fluid 30 ml·kg-1·h-1 can decrease the occurrence of PONV when compared with intravenously infusing fluid 10 ml·kg-1·h-1 in pediatric patients undergoing ambulatory surgery. Key words: Children; Fluid therapy; Postoperative nausea and vomiting; Day care