Abstract
BackgroundCDC’s (Centers for Disease Control and Prevention) National Center for Health statistics recent reports have shown that an upsurge has occurred in the use of dietary supplements among age of 20 years since 1994 and this use shown regular increase. The purpose of our study was to investigate the effect of supplements on the reproductive health on male athletes in Pakistan.MethodsA total of 150 adult male with mean age of 25.78 ± 0.56 years were included in this study and divided into four groups: Non-athlete control (n = 57), Non supplemental athlete control (n = 40), Supplemental athlete group I (n = 28) and supplemental athlete group II (n = 25). Blood (10 ml) was taken from each subject. Complete blood count was performed and 5 ml of blood was centrifuged to separate plasma and then analyzed for antioxidant enzyme (CAT, POD, GR and GSH) activities, Lipid peroxidation (TBARS), electrolyte, metal (sodium, potassium and zinc) and Luteinizing hormone (LH) concentration.ResultsComplete blood count results showed normal RBC, WBC, Platelets, Hemoglobin, Hematocrit, Mean corpuscular hemoglobin and Mean corpuscular hemoglobin concentration. Antioxidant enzymes (CAT, POD, GR, GSH) increased significantly in supplemental athletes as compared to control groups. Sodium and potassium showed significant increase (p < 0.001) in supplemental athlete group I, while TBARS also showed significant increase (p < 0.05) in supplemental group I and II as compared to non athlete control while non supplemental athletes showed significant increase (p < 0.05) in TBARS concentration as compared to non athlete control. LH concentration was found to be decreased significantly (p < 0.05) in supplemental group I and II as compared to control groups.ConclusionIt is therefore concluded from the present results that oxidative stress was considerably elevated in response to supplement consumption among athletes which may affect their health haematological parameters and reproductive hormones.
Highlights
CDC’s (Centers for Disease Control and Prevention) National Center for Health statistics recent reports have shown that an upsurge has occurred in the use of dietary supplements among age of 20 years since 1994 and this use shown regular increase
Athletes are constrained from the use of diverse kinds of nutraceuticals which are habitually used for the treatment of different kind of complacencies as pain management [7], osteoarthritis [8, 9] and ulcerative colitis [10]
The results showed that the body mass index of non-supplemental control, non-supplemental athletes control, supplemental athletes I and II was (23.15 ± 0.44, 26.43 ± 0.56, 26.84 ± 0.72 and 25.77 ± 0.87) which is higher than the body mass index of athletes in WHO global database [27]
Summary
CDC’s (Centers for Disease Control and Prevention) National Center for Health statistics recent reports have shown that an upsurge has occurred in the use of dietary supplements among age of 20 years since 1994 and this use shown regular increase. The frequent use of these supplements is not good for health, studies have shown that continuous use of energy drinks and dietary supplements lead into neurological and cardiovascular problems [4,5,6]. Athletes are constrained from the use of diverse kinds of nutraceuticals which are habitually used for the treatment of different kind of complacencies as pain management [7], osteoarthritis [8, 9] and ulcerative colitis [10]. These nutraceuticals drugs are used by varoius companies. Due to which Athletes are prone to severe health risks, like neurological, metabolic and cardiovascular problems [14,15,16]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
